Get constipation relief in minutes with Fleet Liquid Glycerin Suppositories. The no-mess lubricated Gentle Glide tip inserts rectally to treat constipation at the site of the problem. It generally works within 15-60 minutes. These suppositories will not upset the digestive system. It works by drawing water into the stool to soften and promote a bowel movement. Just insert, squeeze, remove and discard. CONTENTS: 4 Adult Suppositories with saline laxative. 7.5 ml Per tube.